Facing off at Sahlens Stadium, Rochester and New York, the Rattlers took the lead when Matt Streibel buried a two-point shot.
Rochester exploded for six goals in the second quarter, Jordan MacIntosh with the backhander.
Then some great passing, Kevin Leveille to Ned Crotty.
At the end of the third quarter, Crotty hit Leveille for his third goal of the game as the horn sounded.
Defenseman Joel White scored his first two goals of the year.
The Rattlers improve to 4-5 on the year.